Umbilical vessels of preeclamptic women have low contents of both n−3 and n−6 long-chain polyunsaturated fatty acids

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چکیده

منابع مشابه

Synthesis of long-chain polyunsaturated fatty acids in preterm newborns fed formula with long-chain polyunsaturated fatty acids.

BACKGROUND Docosahexaenoic acid (DHA) and arachidonic acid (AA) are long-chain polyunsaturated fatty acids (LCPs) that play pivotal roles in growth and neurodevelopment. OBJECTIVE We aimed to quantify the synthesis of LCPs in preterm infants fed infant formula containing LCPs. DESIGN Twenty-two preterm infants were randomly assigned to either the no-LCP group (fed formula without LCPs; n = ...

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Perinatal biochemistry and physiology of long-chain polyunsaturated fatty acids.

Docosahexaenoic acid (DHA) and arachidonic acid (ARA) are important structural components of the central nervous system. These fatty acids are transferred across the placenta, are present in human milk, and are accumulated in the brain and retina during fetal and infant development. The high concentrations of DHA in the retina and of DHA and ARA in brain gray matter suggests that these fatty ac...

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Long-Chain Polyunsaturated Fatty Acids in Inborn Errors of Metabolism

The treatment of children with inborn errors of metabolism (IEM) is mainly based on restricted dietary intake of protein-containing foods. However, dietary protein restriction may not only reduce amino acid intake, but may be associated with low intake of polyunsaturated fatty acids as well. This review focuses on the consequences of dietary restriction in IEM on the bioavailability of long-cha...

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Significance of long chain polyunsaturated fatty acids in human health

In the last decades, the development of new technologies applied to lipidomics has revitalized the analysis of lipid profile alterations and the understanding of the underlying molecular mechanisms of lipid metabolism, together with their involvement in the occurrence of human disease. Of particular interest is the study of omega-3 and omega-6 long chain polyunsaturated fatty acids (LC-PUFAs), ...

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Placental transfer of long-chain polyunsaturated fatty acids (LC-PUFA).

Considerable evidence exists for marked beneficial effects of omega-3 long-chain polyunsaturated fatty acids (LC-PUFA) during pregnancy. The omega-3 LC-PUFA docosahexaenoic acid (DHA) is incorporated in large amounts in fetal brain and other tissues during the second half of pregnancy, and several studies have provided evidence for a link between early DHA status of the mother and visual and co...

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ژورنال

عنوان ژورنال: The American Journal of Clinical Nutrition

سال: 1999

ISSN: 0002-9165,1938-3207

DOI: 10.1093/ajcn/69.2.293